How is Peyronie’s Disease Treated? SURGERY - XIAFLEX - ANDROPEYRONIE In a very few number of cases (about 13 out of 100), Peyronie's disease goes away without being treated. Many health care experts suggest treating the disease without surgery for the first 12 months after the disease is first noticed. Men with small plaques, not much curving of the penis, no pain, and no problems with sex may not need to be treated. If you need to be treated, there are 3 choices. 1 Surgery for Peyronie's Disease : There are 3 basic ways to fix Peyronie's disease with surgery, but Surgery is not without risks and can include shortening of the penis (scar retraction) and a chance that the distortion will return. COST: $25,000 - $35,000 -making the side of the penis opposite the plaque shorter -making the side of the penis that curves longer -placing a prosthetic device inside the penis https://goo.gl/KfKsUL 2 Penile Injections ( XIAFLEX® )